Renal tubular acidosis in childhood
نویسندگان
چکیده
Increased knowledge on the genetics, the pathophysiology, the natural history and the treatment of renal tubular acidosis (RTA) has begun to clarify this often confusing field. To help pediatricians better acquainted with the physiological and genetic basis of the various types of RTA, to facilitate early diagnosis and treatment with the ultimate aim of preventing the significant growth failure and chronic kidney failure of undiagnosed and untreated patients with RTA, we reviewed new data on the mechanisms of growth retardation in patients with RTA. RTA should be included in the differential diagnosis of a child with growth failure, rickets and metabolic acidosis. The diagnostic work-up and treatment are succinctly presented in this review.
منابع مشابه
Distal Renal Tubular Acidosis with Grade 4 Vesicoureteral Reflux in a Child with Single Kidney
Introduction Renal tubular acidosis (RTA) is a non-uremic defects of urinary acidification. It is characterized by a normal anion gap hyperchloremic metabolic acidosis; plasma potassium may be normal, low or high-depending on the type of RTA. These syndromes differ from uremic acidosis which is associated with a high anion gap, decreased glomerular filtration with enhanced proton secretion b...
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